Oncology

Oncology

Greentech Bioscience developed a biobank of over 200 human- and murine-derived cancer lines, including conventional, resistant, and luciferase-tagged tumor cell lines. Our oncology pharmacology team has strong expertise in establishing a number of in vivo tumor models such as xenograft models and chemically induced tumor models, and conducting in vivo assessment and profiling of immunotherapies.


Human Derived Cell Lines at Greentech Bioscience

Histotype

Cell Lines

Xenograft Models

Conventional

Resistant

Subcutaneous

Orthotopic

Luciferase-tagged

Breast

MCF-7, T47D, BT474, BT-549, HCC1937, HCC1954, MDA-MB-231,  MDA-MB-468, SKBR-3, BT549

MCF-7/ADR, MCF-7/5-FU, MDA-MB-231/Tax

MDA-MB-231-Luc

Lung

H460, HCC827, H1993, H1975, H1650, H1299, H292, A549, PGCL3,   PC-9, L78, H69

A549/CDDP, H460/TP

A549-Luc

Liver

HepG-2, SMMC-7721, MHCC-97H, MHCC-97L, Huh-7, Bel-7402,   Bel-7405, QGY-7701, Bel-7404, SK-HEP-1, Hep-3B

HepG-2/ADM, SMMC-7721/sorafenib

Bel-7402-Luc, SMMC-7721-Luc               

Colon

HCC-116, HCT-15, HCT-8, HT-29, SW480, SW620, LOVO, Caco-2

HCT-8/Vct,HCT-8/Dox, HCT-116/DOX

HCT-116-Luc

Leukemia

K562, K562/IL-13, HL-60, MOLT-4, THP-1, ML-2

K562/ADR,K562/ADM, K562/AO2

/ 

K562-Luc, LAMA84-s-luc

Lymphoma

Raji, Ramos, Jurkat, U937, SUDHL-6

/

Ramos-Luc, MM1S-luc, RPMI-8226-luc

Brain

U87, U251, SH-SY5Y,   SK-N-SH, IMR-32, U118 MG, A172, U87MG, A172

/

U87-Luc, U251-luc,   U87MG-Luc, T98G-luc, LN229-Luc

Gastric

MGC-803, N87, AGS

/

/

Multiple Myeloma

U266, H929, RPMI-8226, MM.1S, OPM-2

/

RPMI-8226-Luc

Ovarian

A2780, SK-OV-3

A2780/Tax

SK-OV-3-Luc

Pancreas

PANC-1, KP4, BXPC-3, CFPAC-1, BON-1, AsPC-1

/

/

/

Prostate

PC-3, DU-145

/

PC-3-Luc

Oral

KB-3-1

KB-3-1/Tax

√ 

/

Osteosarcoma

MG-63, U-2 OS

/

/

MG-63-Luc

Melanoma

A375, SK-MEL-24

/

/

A375-Luc

Esophagus

KYSE-150, TE-1

/

/

/

Bladder

T24, UM-UC-3

/

/

Endocervical

HeLa, SW756

/

/

/

Biliary duct

HuCCT1

/

/

Gallbladder

GBC-SD

/

/

Laryngeal

Hep2

/

/

/

Vulva

A431

/

/

/

Renal

OS-RC-2, Caki-1, 786-O, A498, NCI-H295R

/

/


Murine Derived Cell Lines at Greentech Bioscience

Histotype

Cell Lines

Xenograft Models

Conventional

Resistant

Subcutaneous

Orthotopic

Luciferase-tagged

Breast

MRMT-1, 4T-1

/

4T-1-Luc

Lung

LLC

/

/

Hypophysoma

AtT-20

/

/

/

Colon

MC-38, CT26

/

/

Brain

C6, BV-2

/

C6-Luc

Melanoma

B16F10

/

/

/

Fibrosarcoma

NCTC-2472

/

/

/


Other Animal Models of Oncology

Models

Details

CDX models

Syngeneic Models

Estrogen-dependent breast cancer subcutaneous xenograft model

Mouse model of postsurgical triple-negative breast cancer recurrence

Mouse model of primary tumor models

Chemically induced tumor models

DEN induced primary liver cancer model

AOM/DSS induced colon cancer mouse model

Humanized immune checkpoint mouse models

Humanized PD-1 mouse model

Humanized CTLA-4 mouse model

Humanized mouse model

Humanized PBMC mouse model

Radiation therapy model

Tumor model of radiation treatment combined with other therapies


Inquiries

Request a quote now, or email us at BD@greentech-bio.com to inquire about our services or obtain a quote for your project.