Bone, Joint & Cartilage Diseases
In the field of bone, joint and cartilage diseases, Greentech Bioscience offers several validated animal models of bone and joint diseases for drug efficacy testing. We can also customize in vivo models according to customers’ requirements. Additionally, we provide efficacy testing and biocompatibility testing of bone biomaterials.
Figure 1. In vivo pharmacology platform of bone, joint and cartilage diseases at Greentech.
Our Animal Models for Bone and Joint Diseases
Diseases | Animal Models | Species | Clinical Assessment |
Ovariectomy induced primary osteoporosis | Rats, rabbits, NHPs | (1) microCT: BMD, Tb.N, Tb.Sp, Tb.Th, BV/TV (2) Biomechanics (3) Bone turnover markers | |
Glucocorticoid induced secondary osteoporosis | |||
MIA induced osteoarthritis | Mice, rats, rabbits | (1) Pain assessment (2) Serum/Synovial marker detection (3) Histopathology (4) Gait analysis and motor function (5) Micro-CT | |
Medial meniscal transection (MMT) | Rats | ||
Anterior cruciate ligament transection (ACLT) | Rabbits | ||
Meniscal injury | Rabbits |
Inquiries
Request a quote now, or email us at BD@greentech-bio.com to inquire about our services or obtain a quote for your project.
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