Models of Cardiac Arrhythmia

Cardiac arrhythmia is a common cause of mortality. Greentech Bioscience is proud to offer epinephrine-induced arrhythmia model to help clients investigate the pathological mechanisms and screen novel drugs.

Epinephrine-Induced Arrhythmia Model

Induction: slow intravenous injection of epinephrine

Species: rats, rabbits, etc.

Disease characteristics: induction of multifocal premature beats and paroxysmal supraventricular tachycardia (PSVT)

Clinical Assessment

Ultrasonic cardiogram

12-lead electrocardiogram

Blood pressure monitoring by tail-cuff

Basic Service

Body weight, food intake, excretion

Blood collection and tissue collection

Histopathology

Inquiries

Request a quote now, or email us at BD@greentech-bio.com to inquire about our services or obtain a quote for your project.

References

1. Y.Sarne, I.Hochman, M.Eshed,E Oppenheimer.(1988) Antiarrhythmic action of naloxone: Direct, non-opiate effect on the rat heart. Life Sciences.Volume 43, Issue 10, Pages 859-864.

2. Hamlin, R. L. (2007). Animal models of ventricular arrhythmias. Pharmacology & Therapeutics, 113(2), 276–295.

3. Dobrev, D., & Wehrens, X. H. T. (2018). Mouse Models of Cardiac Arrhythmias. Circulation Research, 123(3), 332–334.