Psychiatry & Neurology
Greentech Bioscience boasts years of experience in pharmacology and pharmacodynamics. In the field of psychiatric disorders and neurologic diseases, we have established a number of validated animal models for assessment of different therapeutic approaches, ensuring high quality, reproducible data. We can also develop novel models according to clients’ requirements.
Our Animal Models in Psychiatry and Neurology
Diseases | Animal Model | Species | Clinical Assessment |
Unilateral carotid artery occlusion HIE model | SD rats | (1) Neurological evaluation (2) Brain weight (3) Histopathology (4) Behavioral tests | |
Tracheal occlusion HIE model | SD rats | ||
Controlled cortical impact (CCI) model | Mice, SD rats | (1) Blood pressure (2) Body temperature (3) Neurological Severity Scores (4) Behavioral tests (5) Histopathology (6) IHC | |
MPTP induced model | Mice, NHPs | (1) Blood routine and biochemistry (2) Open field, Pole test (3) MRI imaging (4) Biomarker analysis (5) Histopathology, IHC | |
6-OHDA lesion model | Rats | ||
Alpha-synuclein transgenic mice | Mice | ||
APP/PS1 transgenic mice | Mice | (1) Neurobehavioral testing (2) Aβ detection (3) Tau protein detection (4) IHC (5) Detection of AChE, ChAT, Ach (6) Neuroinflammation detection (7) Oxidative stress detection | |
SAMP8 mice | Mice | ||
Scopolamine induced Model | Mice, rats | ||
Light/dark box test | Mice, rats | (1) Light chamber time (2) Dark chamber time (3) Number of cross | |
Elevated plus maze test | Mice, rats | (1) Open arm time (2) Open arm entry (3) Closed arm entry (4) Closed arm time | |
Tail suspension test | Mice | Immobility time | |
Forced swim test | Mice, rats |
Behavioral Testing Platform
The behavioral testing platform at Greentech Bioscience consists of learning, memory and cognitive tests, anxiety and depression tests, as well as motor and sensory tests, enabling us to conduct preclinical pharmacological evaluation of different therapeutic approaches for psychiatric disorders and neurologic diseases.
Figure 1. Behavioral testing platform at Greentech Bioscience.
Inquiries
Request a quote now, or email us at BD@greentech-bio.com to inquire about our services or obtain a quote for your project.
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