Greentech Bioscience has established a tumor cell bank comprising over 100 human- or rodent-derived cell lines for research purposes. Our cell line-derived xenograft models can be established by subcutaneous or orthotopic transplant in mice with an intact or deficient immune system. CDX model is the gold-standard for the research and assessment of anti-cancer therapies.
Greentech has established over 100 subcutaneous xenograft mouse models and orthotopic xenograft mouse models. Click our tumor cell bank to get more information about our CDX mouse models.
1. Estrogen-dependent breast cancer MCF-7 xenograft mouse model and therapeutic efficacy research of paclitaxel (Taxol)
2. Neuroglioma U87-MG-Luc orthotopic tumor model
3. CAR-T therapy assessment in severe immunodeficient mice injected with human multiple myeloma cells
Induction: subcutaneous administration of 5×106 RPMI-8226 cells/mice
Dosage regimen: treatments were given after tumor volumes reaches 80 mm3, qd for 2 days, iv.