Bioanalytics is an essential tool for determining the concentration of biomarkers, drugs and their metabolites in various biological fluids. Bioanalytical method validation serves as a critical step ensuring that quantitative data demonstrate selectivity, accuracy and stability. Greentech provides high quality small molecule bioanalysis services, including development and validation of LC-MS/MS methods, method transfer, and quantitative sample analysis in human and animal matrices (plasma, tissues, urine and feces), contributing to preclinical and clinical development of small molecule drugs.
Bioanalytical method development/validation/transfer
Calibration curve and lower limit of quantification
Accuracy and precision
Quantitative analysis of biomarkers, drugs and toxins in biological samples
Figure 1. Typical validation of selectivity.
Figure 2. Accuracy and precision values of the HPLC-MS/MS method for the determination of a compound in rat plasma.