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GreenTech's Histopathology Platform Supporting Preclinical Drug Development!

Time:2024-10-18 Author:This site Views:153

Sichuan Greentech Bioscience offers a comprehensive histopathology platform equipped with advanced tissue processing, sectioning, and imaging equipment. Our team includes several technicians and certified veterinary pathologists, with many years of industry experience. We provide a range of histological services, including paraffin sectioning, frozen sectioning, immunohistochemistry (IHC), immunofluorescence (IF), fluorescence in situ hybridization (FISH), hematoxylin and eosin (HE) staining, and special staining. In addition, we offer professional histopathological diagnostic services and have successfully advanced nearly 40 drug candidates into clinical trials.

Currently, our pathology diagnostic platform employs two full-time professional veterinary pathologists along with several external pathology experts. We specialize in toxicological pathology evaluations for various tissues and organs, as well as preclinical pharmacodynamic pathology evaluations for plenty of disease models in animals. So far, our team have completed pathological diagnosis of tens of thousands of slides. The platform has established semi-quantitative or quantitative standards for pathological diagnosis and pathological atlases of major human disease models to provide more reliable references for preclinical pharmacodynamic evaluations from a comparative pathology perspective, aiding clinical translation.


Table 1. Greentech histopathology platform service content.

Species research experiencesMice, rats, transgenic mice, guinea pigs, rabbits, pigs, dogs, NHPs
Slide typesFrozen section, paraffin section, bone decalcification, immunohistochemistry, immunofluorescence, TUNEL, fluorescence in situ hybridization, HE staining, various special stains
Estanblishment of pathological diagnostic creteriaDigestive and metabolic diseases, inflammatory and immune diseases, neurological diseases, cardio-cerebrovascular diseases, pain and analgesia, bone and joint diseases, urogenital diseases, tumors, toxicologic pathology, efficacy testing of medical devices
Digital pathology scanning
20x scanning, 40x scanning, bright-field scanning


 

Case Study

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