Oncology

Cell Lined-Derived Xenograft (CDX) Models

Greentech Bioscience has established a tumor cell bank comprising over 100 human- or rodent-derived cell lines for research purposes. Our cell line-derived xenograft models can be established by subcutaneous or orthotopic transplant in mice with an intact or deficient immune system. CDX model is the gold-standard for the research and assessment of anti-cancer therapies.


Our CDX Models

Greentech has established over 100 subcutaneous xenograft mouse models and orthotopic xenograft mouse models. Click our tumor cell bank to get more information about our CDX mouse models.


Case Study

1. Estrogen-dependent breast cancer MCF-7 xenograft mouse model and therapeutic efficacy research of paclitaxel (Taxol)

Estrogen-dependent breast cancer MCF-7 xenograft model.png

Estrogen-dependent breast cancer MCF-7 xenograft model.png


2. Neuroglioma U87-MG-Luc orthotopic tumor model

Neuroglioma U87-MG-Luc orthotopic tumor model.png

Neuroglioma U87-MG-Luc orthotopic tumor model.png


3. CAR-T therapy assessment in severe immunodeficient mice injected with human multiple myeloma cells

Induction: subcutaneous administration of 5×106 RPMI-8226 cells/mice

Dosage regimen: treatments were given after tumor volumes reaches 80 mm3, qd for 2 days, iv.

CAR-T therapy assessment on severe immunodeficient mice injected with human multiple myeloma cells.png


Inquiries

Request a quote now, or email us at BD@greentech-bio.com to inquire about our services or obtain a quote for your project.